Within a population of alleles at a locus, there arise several mutant alleles. The selection coefficient of the mutants are as follows:
(a) If selection were the only evolutionary force acting in a system, which of these mutants would be most represented in the next generation? Why?
(b) In a population of Ne = 2500, which of these mutants will be considered functionally neutral, under Ohta’s nearly-neutral model?
(c) What about Ne = 25?
(d) Explain the difference between your answers in (b) and (c) in terms of the drift-selection balance i.e. relative strength of genetic drift to selection.