Myotonic dystrophy is an autosomal recessive disorder affecting 1 in 500 people in Quebec.What are the expected frequencies for the dominant and

  1. Myotonic dystrophy is an autosomal recessive disorder affecting 1 in 500 people in Quebec. What are the expected frequencies for the dominant and recessive alleles in the Quebec population?

a.   Dominant?

b.   Recessive?

c.   What percent of the Quebec population would you expect to be homozygous for the normal (non-disease) allele?

d.   Myotonic dystrophy affects one in 7500 people in all of Canada. What would be the expected frequency of carriers of myotonic dystrophy in Canada?

e.   Assuming the population of Canada is 30 million people, what number of people in Canada would you expect to be carriers?

1.   If 36% of the population has a phenotype that shows the dominant trait:

a.   What is the frequency of the dominant allele?

b.   What is the frequency of the recessive allele?

c.   What % of the population will have the recessive trait?

  1. d.   What % of the population will be heterozygous?