Hi, need to submit a 5000 words essay on the topic Retroanalyses nonrandomized study over a X period of time for esophageal cancer patient which compares two treatment options: intra-luminal brachytherapy alone vs. intra-luminal brachytherapy treatment combined with chemotherapy.
Esophageal cancer is a very devastating disease (Gibson et al. 1564). This among others is factors that championed for the reason and purpose of this research study.
Although esophageal cancer may be cured in some patients, esophageal cancer treatment is very protracted. It decreases the quality of the life of the victim and is often lethal in several cases. The idyllic treatment of esophageal cancer is actually debatable. In fact, some defendants of surgical treatment have argued that resection is the only modality treatment to provide curative intent. however, the defendant of non surgical approach have claimed that esophageal cancer is particularly incurable and that esophagectomy pose a prohibitive index of mortality. Adenocarcinoma of the esophagus which is specifically different from the squamous cell carcinoma has effects on the distal esophagus of the patients and is normally detected in its initial stages. These facts about esophageal cancer has altered the natural history of surgical treatment in the population of young patient, making its cure a reality. Historically, there has been a well description of esophageal carcinoma since the early 19th Century. The first resection that was successful was conducted by Frank Torek in 1913. This was followed by Ohsawa and Marshall who performed the first transthoracic esophagectomy in Japan and united States respectively with the reconstruction of the continent (Van Cutsem et al. 14991).
According to recent studies, 90% of esophageal cancers are advanced locally at diagnosis, and its treatment brings about discouraging results. The rate of high dose brachytherapy (HDR-BT) allows an increment of the local doses with no particular significant toxic increment. Esophageal cancer has continued to pose a threat globally to the health of the public. The commonly witnessed practice is radiochemotherapy for unresectable tumors that have