# Disease X is one that often results in severe illness but is never fatal

## Disease X is one that often results in severe illness but is never fatal

Disease X is one that often results in severe illness but is never fatal

Disease X is one that often results in severe illness but is never fatal. On March 21, 2002, 30 students enrolled in an introductory epidemiology course at a university developed disease X. Assume all epidemiology students were exposed to the index case, the instructor.

Through antibody titers we were able to determine the following (antibody titers measure the concentration of antibodies in individuals and can be used to provide evidence of infection):

# of exposed students not infected                                  40

# of exposed students with subclinical infection              10

# of exposed students with mild symptoms                     10

# of exposed students with moderate symptoms             10

# of exposed students with severe symptoms                  10

Using your knowledge of infectious disease epidemiology, quantify the pattern of disease X in this group; that is, what are the infectivity and virulence of disease X?

1. Imagine you are the State Epidemiologist. Sixty cases of salmonella were reported to you in the last two weeks. Describe how the iceberg model of disease would argue for or against about this potential disease outbreak needs to be investigated.

Part 1:

To get the infectivity and virulence of disease X we do the following

a. # of exposed students not infected = 40
To get Not Infected, we have
Number of ill students (30) + number of students not infected (40) = Total Attack rate …

APA

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