Compose a 2000 words essay on Stem cell treatment for parkinsons disease to produce dopaminergic neurons. Needs to be plagiarism free!
Specifically, scientists have established that PD affects specific neurons that produce dopamine in the brain. Since the disease kills these dopamine producing neurons, stem cells provide a potential solution for replacing the dopamine producing neurons. Scientists can use specific stem cells to produce dopamine-producing neurons in vitro. Kriks et al., (2011) stated that engaftable DA neurons can survive in vitro for months. Through previous stem cell studies, researchers have established the embryonic and fetal neurons can be used to reverse the effects of PD on the dopamine producing neurons in the brain. This enables them to study the disease in depth. Moreover, the laboratory produced cells can them be introduced into the affected PD patients such that they replace the damaged ones and cause a reversal of the Parkinson’s disease. These studies are yet to be conducted on humans because of the uncertainties and side effects realized. However, their findings provide hope that stem cells can provide the much needed treatment for Parkinson’s disease. This paper presented an annotated bibliography of 10 research papers on the subject of stem cell treatment for Parkinson’s disease to produce dopaminergic neurons.The research studies present various findings that support the potential of stem cell treatment for PD to produce dopaminergic neurons, which are killed by the disease. However, the studies also present other findings related to the potential and efficiency of stem cell treatment for PD.
Cova, L., Armentero, M., Zennaro, E., Calzarossa, C., Bossolasco, P. et al. 2010.‘Multiple neurogenic and neurorescue effects of human mesenchymal stem cell after transplantation in an experimental model of Parkinson’s disease.’Brain Research, vol. 1311, pp. 12-27.
The purpose of this study was to explore the neurogenic as well as